Article
Association between neuropeptide Y gene and its receptor Y1 gene and methamphetamine dependence.
Psychiatry and clinical neurosciences - 1 Jun 2009
Okahisa Yuko, Ujike Hiroshi, Kotaka Tatsuya, Morita Yukitaka, Kodama Masafumi, Inada Toshiya, Yamada Mitsuhiko, Iwata Nakao, Iyo Masaomi, Sora Ichiro, Ozaki Norio, Kuroda Shigetoshi
Abstract excerpt
AIMS: Neuropeptide Y (NPY) is a 36-amino acid peptide that is widely distributed in the brain, adrenal medulla, and sympathetic nervous system. Several lines of evidence suggest a possible involvement of the NPY system in the physiological effects of several classes of abused substances including alcohol, phencyclidine, cocaine, and marijuana and in endogenous psychosis. Accordingly, it was hypothesized that the...
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