Article
Oncogenic virus-associated neoplasia: a role for cyclin D1 genotypes influencing the age of onset of disease?
Biochemical and biophysical research communications - 23 May 2008
Catarino R, Pereira D, Breda E, Coelho A, Matos A, Lopes C, Medeiros R
Abstract excerpt
Cyclin D1 (CCND1) is a key regulatory protein at the G1/S checkpoint of the cell cycle. The purpose of our study was to assess the role of CCND1 genotypes influencing the age of onset of oncogenic virus-associated neoplasia. We conducted a hospital-based case-control study of 581 individuals, including 247 controls and 334 cases (108 nasopharyngeal and 226 cervical cancer cases). The polymorphism analysis was...
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