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Article

An update on the implications of cyclin D1 in oral carcinogenesis

15 Dec 2016

Abstract excerpt

Cyclin D1 promotes cell cycle progression during G1 phase, a key event in G1-S transition. The protein is encoded by gene CCND1, located in chromosomal band 11q13. Cyclin D1 plays key roles in cell biology, including cell proliferation and growth regulation, mitochondrial activity modulation, DNA repair, and cell migration control. CCND1 gene and its protein cyclin D1 are frequently altered by different molecular...

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PMID: 27973759
DOI: 10.1111/odi.12620

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