Article
Cyclin D1 polymorphism and the risk of endometrial cancer.
Gynecologic oncology - 1 May 2005
Kang Sokbom, Kim Jae Weon, Park Noh Hyun, Song Yong Sang, Kang Soon Beom, Lee Hyo Pyo
Abstract excerpt
OBJECTIVES: The common G to A single nucleotide polymorphism (G870A) in the splice donor region of exon 4 enhances alternate splicing, and produces a longer half-life cyclin D1 (CCND1). This study was aimed at investigating the possible association between the G870A polymorphism in CCND1 and the risk of endometrial cancer. METHODS: We assessed the association between the CCND1 G870A polymorphism and the risk of...
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