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Article

Inducing antitumor T cell immunity: comparative functional analysis of interstitial versus Langerhans dendritic cells in a human cell line model.

Journal of immunology (Baltimore, Md. : 1950) - 1 Apr 2008

Santegoets Saskia J A M, Bontkes Hetty J, Stam Anita G M, Bhoelan Farien, Ruizendaal Janneke J, van den Eertwegh Alfons J M, Hooijberg Erik, Scheper Rik J, de Gruijl Tanja D

Abstract excerpt

Dendritic cells (DC) are increasingly applied as a cellular adjuvant in immunotherapy of cancer. Two major myeloid DC subsets are recognized: interstitial DC (IDC) that infiltrate connective tissues and Langerhans cells (LC) that line epithelial surfaces. Yet, functional differences between IDC and LC remain to be defined. We recently showed that the CD34(+) acute myeloid leukemia cell line MUTZ-3 supports...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18354176
DOI: 10.4049/jimmunol.180.7.4540

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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