Article
Plasmid-borne prokaryotic gene expression: sources of variability and quantitative system characterization.
Physical review. E, Statistical, nonlinear, and soft matter physics - 1 Feb 2008
Bagh Sangram, Mazumder Mostafizur, Velauthapillai Tharsan, Sardana Vandit, Dong Guang Qiang, Movva Ashok B, Lim Len H, McMillen David R
Abstract excerpt
One aim of synthetic biology is to exert systematic control over cellular behavior, either for medical purposes or to "program" microorganisms. An engineering approach to the design of biological controllers demands a quantitative understanding of the dynamics of both the system to be controlled and the controllers themselves. Here we focus on a widely used method of exerting control in bacterial cells: plasmid...
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