Article

Host-specific plasmid evolution explains the variable spread of clinical antibiotic-resistance plasmids

2022-07-07

Abstract excerpt

Antibiotic resistance encoded on plasmids is a pressing global health problem. Predicting which plasmids spread/decline in the long term remains a huge challenge, even though some key parameters influencing plasmid stability have been identified, such as plasmid growth costs and horizontal transfer rates. Here, we show these parameters evolve in a strain-specific way among clinical plasmids/bacteria, and this occu...

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Literature Corpus work: c53d080a-5604-5893-8c66-ddc935877f43
DOI: 10.1101/2022.07.06.498992

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