Ecological theory sheds light on plasmid diversity and dynamics.

doi:10.1371/journal.pbio.3003918

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Ecological theory sheds light on plasmid diversity and dynamics.

PLoS biology - 1 Aug 2026

Tuffet Rémi, Acacia Emma, Coluzzi Charles, Charpentier Xavier, Koffel Thomas, Venner Samuel

Abstract excerpt

Bacterial genomes are remarkably dynamic, shaped by horizontal gene transfer. Plasmids are key actors in this process, fueling rapid bacterial adaptation to stresses such as antibiotics. Yet, plasmids follow evolutionary trajectories of their own, defying traditional genetic frameworks. Beyond the co-evolution of traits directly involved in plasmid-host relationships, it is now essential to draw from ecological...

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PMID: 42664264
DOI: 10.1371/journal.pbio.3003918
PMCID: PMC13524261

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