Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cognitive performance in neurokinin 3 receptor knockout mice.

Psychopharmacology - 1 Jun 2008

Nordquist R E, Delenclos M, Ballard T M, Savignac H, Pauly-Evers M, Ozmen L, Spooren W

Abstract excerpt

RATIONALE: The neurokinin 3 (NK(3)) receptor is a novel target under investigation for improvement of the symptoms of schizophrenia due to its ability to modulate dopaminergic signaling. However, research on effects of NK(3) antagonism with animal models has been hindered because of species differences in the receptor between humans, rats, and mice. OBJECTIVES: The aim of the present study is to further knowledge...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cloning, Molecular
Share to Cognition
Share to Conditioning, Operant

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Maze Learning

Share to Memory, Short-Term

Share to Mice, Knockout

Share to Reinforcement, Psychology

Share to Space Perception

Source

Identifiers

PMID: 18351324
DOI: 10.1007/s00213-008-1119-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cognitive performance in neurokinin 3 receptor knockout mice.PMID 18351324Read ↗

Neurokinin3 receptor as a target to predict and improve learning and memory in the aged organism.Semantic proximity Read ↗

Perseveration by NK1R-/- ('knockout') mice is blunted by doses of methylphenidate that affect neither other aspects of their cognitive performance nor the behaviour of wild-type mice in the 5-Choice Continuous Performance Test.Semantic proximity Read ↗

A lack of functional NK1 receptors explains most, but not all, abnormal behaviours of NK1R-/- mice(1).Semantic proximity Read ↗

Disturbances of novel object exploration and recognition in a chronic ketamine mouse model of schizophrenia.Semantic proximity Read ↗

Cognition in transmembrane domain neuregulin 1 mutant mice.Semantic proximity Read ↗

Behavioural and neurochemical abnormalities in mice lacking functional tachykinin-1 (NK1) receptors: a model of attention deficit hyperactivity disorder.Semantic proximity Read ↗

Affective and cognitive effects of global deletion of alpha3-containing gamma-aminobutyric acid-A receptors.Semantic proximity Read ↗

Differences in spatial learning comparing transgenic p75 knockout, New Zealand Black, C57BL/6, and Swiss Webster mice.Semantic proximity Read ↗

Characterization of cognitive deficits in mice with an alternating hemiplegia-linked mutation.Semantic proximity Read ↗

Spatial learning deficit in dopamine D(1) receptor knockout mice.Semantic proximity Read ↗

Comprehensive behavioral analysis of indoleamine 2,3-dioxygenase knockout mice.Semantic proximity Read ↗

Phenotypic characterization of cognition and social behavior in mice with heterozygous versus homozygous deletion of catechol-O-methyltransferase.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.