Article
Characterization of cognitive deficits in mice with an alternating hemiplegia-linked mutation.
Behavioral neuroscience - 1 Dec 2015
Kirshenbaum Greer S, Dachtler James, Roder John C, Clapcote Steven J
Abstract excerpt
Cognitive impairment is a prominent feature in a range of different movement disorders. Children with Alternating Hemiplegia of Childhood are prone to developmental delay, with deficits in cognitive functioning becoming progressively more evident as they grow older. Heterozygous mutations of the ATP1A3 gene, encoding the Na+,K+-ATPase α3 subunit, have been identified as the primary cause of Alternating...
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