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Article

High genetic stability of dengue virus propagated in MRC-5 cells as compared to the virus propagated in vero cells.

PloS one - 19 Mar 2008

Liu Chia-Chyi, Lee Shiang-Chi, Butler Michael, Wu Suh-Chin

Abstract excerpt

This work investigated the replication kinetics of the four dengue virus serotypes (DEN-1 to DEN-4), including dengue virus type 4 (DEN-4) recovered from an infectious cDNA clone, in Vero cells and in MRC-5 cells grown on Cytodex 1 microcarriers. DEN-1 strain Hawaii, DEN-2 strain NGC, DEN-3 strain H-87, and DEN-4 strain H-241 , and DEN-4 strain 814669 derived from cloned DNA, were used to infect Vero cells and...

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Identifiers

PMID: 18350148
DOI: 10.1371/journal.pone.0001810
PMCID: PMC2265545

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