Article
Development and Characterization of a Genetically Stable Infectious Clone for a Genotype I Isolate of Dengue Virus Serotype 1.
Viruses - 18 Sept 2022
Hu Mingyue, Wu Tiantian, Yang Yang, Chen Tongling, Hao Jiawei, Wei Youchuan, Luo Tingrong, Wu De, Li Yi-Ping
Abstract excerpt
Dengue virus (DENV) is primarily transmitted by the bite of an infected mosquito of Aedes aegypti and Aedes albopictus, and symptoms caused may range from mild dengue fever to severe dengue hemorrhagic fever and dengue shock syndrome. Reverse genetic system represents a valuable tool for the study of DENV virology, infection, pathogenesis, etc. Here, we generated and characterized an eukaryotic-activated...
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