Article
Model for kinetics of wild-type and mutant kinesins.
Bio Systems - 1 Apr 2006
Xie Ping, Dou Shuo-Xing, Wang Peng-Ye
Abstract excerpt
A hand-over-hand model is presented for the processive movement of two-headed kinesin based on previous structural and biochemical studies. In the model, the ATPase activities of the two heads are regulated by forces, both from internal elasticity and external load, exerted on their neck linkers....
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