Article
HLA-DQB1*06:02 allele frequency and clinic-polysomnographic features in Saudi Arabian patients with narcolepsy.
Sleep & breathing = Schlaf & Atmung - 1 Mar 2019
Al Shareef Saad M, AlAnbay Eiman, AlKhathlan Mujahed A, Shakoor Zahid, Alnasser Mustafa, Hamam Khalid D, Alharbi Adel S, Almeneessier Aljohara S, BaHammam Ahmed S
Abstract excerpt
BACKGROUND: Narcolepsy is an uncommon neurological disorder characterised by irresistible spells of sleep associated with abnormal rapid eye movement (REM) sleep. The association between narcolepsy and human leukocyte antigen HLA- DQB1*06:02 has been established elsewhere but remains to be investigated among Saudi Arabian patients with narcolepsy. METHODS: A total of 29 Saudi patients with type I or type 2...
Topics
- Adolescent
- Adult
- Arabs
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- HLA-DQ beta-Chains
- Humans
- Male
- Narcolepsy
- Polysomnography
