No association between migraine and HLA alleles in a cohort of 13,210 individuals with migraine from the Danish Blood Donor Study.

doi:10.1111/head.14784

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No association between migraine and HLA alleles in a cohort of 13,210 individuals with migraine from the Danish Blood Donor Study.

Headache - 1 Jan 2025

Tummoszeit Inga Zalia, Olofsson Isa Amalie, Chalmer Mona Ameri, Henriksen Alexander Pil, Aagaard Bitten, Brunak Søren, Bruun Mie Topholm, Didriksen Maria, Erikstrup Christian, Hjalgrim Henrik, Mikkelsen Christina, Mikkelsen Susan, Ostrowski Sisse Rye, Pedersen Ole Birger Vesterager, Quinn Liam, Sørensen Erik, Ullum Henrik, Olesen Jes, Banasik Karina, Hansen Thomas Folkmann, Kogelman Lisette J A

Abstract excerpt

OBJECTIVE: To determine the association between human leukocyte antigen (HLA) alleles and migraine, migraine subtypes, and sex-specific factors. BACKGROUND: It has long been hypothesized that inflammation contributes to migraine pathophysiology. This study examined the association between migraine and alleles in the HLA system, a key player in immune response and genetic diversity. METHODS: We performed a...

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PMID: 39352055
DOI: 10.1111/head.14784
PMCID: PMC11726007

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