Article
Genetic variations of the NR3C1 gene in children with sporadic nephrotic syndrome.
Biochemical and biophysical research communications - 22 Sept 2006
Ye Jianwei, Yu Zihua, Ding Jie, Chen Yan, Huang Jianping, Yao Yong, Xiao Huijie, Yang Jiyun, Shen Ying, Meng Qun
Abstract excerpt
Previous studies have demonstrated that the genetic variations of glucocorticoid receptor gene (NR3C1) are associated with both familial steroid resistance and acquired steroid resistance in some diseases, such as Cushing's disease, leukemia, lupus nephritis, and female pseudohermaphroditism. In this study, we examined the genetic variations of NR3C1 in 35 children with sporadic steroid-resistant nephrotic...
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