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Article

Molecular phenotypic descriptors of Dupuytren's disease defined using informatics analysis of the transcriptome.

The Journal of hand surgery - 1 Mar 2008

Rehman Samrina, Salway Fiona, Stanley John K, Ollier William E R, Day Philip, Bayat Ardeshir

Abstract excerpt

PURPOSE: Dupuytren's disease (DD) is a fibroproliferative disorder of unknown etiopathogenesis, which may cause progressive, permanent contracture of digits. Previous studies provide compelling evidence that genetic alterations play an important role. Macroscopically affected areas demonstrate phenotypic differences between the two structurally distinct fibrotic elements in DD (ie, the nodule and the cord). In...

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Source

Identifiers

PMID: 18343292
DOI: 10.1016/j.jhsa.2007.11.010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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