Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of differentially expressed genes in fibroblasts derived from patients with Dupuytren's Contracture

23 Apr 2008

Abstract excerpt

Dupuytren's contracture (DC) is the most common inherited connective tissue disease of humans and is hypothesized to be associated with aberrant wound healing of the palmar fascia. Fibroblasts and myofibroblasts are believed to play an important role in the genesis of DC and the fibroproliferation and contraction that are hallmarks of this disease. This study compares the gene expression profiles of fibroblasts...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dupuytren's Contracture and Treatments
Share to Genital Health and Disease
Share to Orthopedic Surgery and Rehabilitation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18433489
DOI: 10.1186/1755-8794-1-10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of differentially expressed genes in fibroblasts derived from patients with Dupuytren's ContracturePMID 18433489Read ↗

Fibroblasts from phenotypically normal palmar fascia exhibit molecular profiles highly similar to fibroblasts from active disease in Dupuytren's Contracture.Semantic proximity Read ↗

Genome-Wide Analysis Using Exon Arrays Demonstrates an Important Role for Expression of Extra-Cellular Matrix, Fibrotic Control and Tissue Remodelling Genes in Dupuytren's DiseaseSemantic proximity Read ↗

Molecular phenotypic descriptors of Dupuytren's disease defined using informatics analysis of the transcriptome.Semantic proximity Read ↗

Deciphering Mesenchymal Drivers of Human Dupuytren’s Disease at Single-Cell LevelSemantic proximity Read ↗

A Genome-wide Association Study of Dupuytren Disease Reveals 17 Additional Variants Implicated in Fibrosis.Semantic proximity Read ↗

Identification of biomarkers in Dupuytren's disease by comparative analysis of fibroblasts versus tissue biopsies in disease-specific phenotypes.Semantic proximity Read ↗

A meta-analysis of genome-wide association studies in 614,243 individuals identifies 59 novel susceptibility loci underlying Dupuytren’s contractureSemantic proximity Read ↗

Microarray gene analysis and expression profiles of Dupuytren's contracture.Semantic proximity Read ↗

Molecular genetics of Dupuytren’s contractureSemantic proximity Read ↗

Recent advances in the understanding of Dupuytren’s diseaseSemantic proximity Read ↗

Dupuytren's disease susceptibility gene, EPDR1, is involved in myofibroblast contractility.Semantic proximity Read ↗

Investigating the genetic basis of fibrotic pathway dysregulation in Dupuytren's contracture.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.