Article
Microarray gene analysis and expression profiles of Dupuytren's contracture.
Annals of plastic surgery - 1 Jun 2003
Pan Deborah, Watson H Kirk, Swigart Carrie, Thomson J Grant, Honig Stanton C, Narayan Deepak
Abstract excerpt
Dupuytren's disease, although not altogether uncommon, has eluded scientists who have sought to explain the cause of this palmar fibroproliferative disorder. It can lead to severe limitations of hand function if left untreated. This study is the first broad genetic survey using microarray technology to find gene products that are overexpressed or underexpressed in diseased tissues. The authors found 23 genes with...
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