Article
Matrix metalloproteinase-3 (MMP3) and MMP9 genes and risk of myocardial infarction, ischemic stroke, and hemorrhagic stroke.
Atherosclerosis - 1 Nov 2008
Kaplan Robert C, Smith Nicholas L, Zucker Stanley, Heckbert Susan R, Rice Kenneth, Psaty Bruce M
Abstract excerpt
OBJECTIVE: We assessed the association of genetic variation in MMP3 and MMP9 with risk of myocardial infarction and stroke. METHODS: A case-control study was conducted among members of Group Health (GH), a large-integrated health care delivery system. Case subjects with incident non-fatal myocardial infarction (n=854), ischemic stroke (n=367), and hemorrhagic stroke (n=66) were identified and validated. A matched...
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