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Article

Family-based association study of matrix metalloproteinase-3 and -9 haplotypes with susceptibility to ischemic white matter injury.

Human genetics - 1 Jan 2007

Fornage Myriam, Mosley Thomas H, Jack Clifford R, de Andrade Mariza, Kardia Sharon L R, Boerwinkle Eric, Turner Stephen T

Abstract excerpt

Susceptibility to ischemic damage to the subcortical white matter of the brain has a strong genetic basis. Dysregulation of matrix metalloproteinases (MMPs) contributes to loss of cerebrovascular integrity and white matter injury. We investigated whether sequence variation in the genes encoding M...

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Identifiers

PMID: 17024375
DOI: 10.1007/s00439-006-0236-8

Genes

MMP3
MMP9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17024375-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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