Article
Matrix metalloproteinase-3 gene polymorphisms are associated with ischemic stroke.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 Feb 2012
Kim Su Kang, Kang Sung Wook, Kim Dong Hwan, Yun Dong Hwan, Chung Joo-Ho, Ban Ju Yeon
Abstract excerpt
Stroke is a heterogeneous disease caused by different pathogenic mechanisms. Several candidate genes for stroke have been proposed, but few have been replicated. Matrix metalloproteinases (MMPs) are expressed following stroke. We investigated the association of single nucleotide polymorphisms (SNPs) of the MMP3 gene with stroke in the Korean population. This study included 186 stroke patients [116 ischemic stroke...
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