Article
Molecular alterations of Barrett's esophagus on microdissected endoscopic biopsies.
Laboratory investigation; a journal of technical methods and pathology - 1 Feb 2001
Romagnoli S, Roncalli M, Graziani D, Cassani B, Roz E, Bonavina L, Peracchia A, Bosari S, Coggi G
Abstract excerpt
Alterations in proto-oncogenes and tumor suppressor genes play a role in the sequence from Barrett's metaplasia to esophageal adenocarcinoma. The present study aims to ascertain whether molecular abnormalities take place in Barrett's metaplasia and low-grade dysplasia and to correlate them with the histological features of the esophageal mucosa. Forty-one formalin-fixed, paraffin-embedded endoscopic esophageal...
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