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Article

Genetic pathways involved in the progression of Barrett's metaplasia to adenocarcinoma.

The British journal of surgery - 1 Jul 2002

Jenkins G J S, Doak S H, Parry J M, D'Souza F R, Griffiths A P, Baxter J N

Abstract excerpt

BACKGROUND: The prediction of which patients with Barrett's metaplasia will develop cancer is difficult. Better genetic characterization of the condition may aid clinicians in devising more effective management and follow-up strategies. METHODS: A review was undertaken of the accumulated genetic data relating to the progression of squamous epithelium to adenocarcinoma. The normal functions of a number of...

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PMID: 12081731
DOI: 10.1046/j.1365-2168.2002.02107.x

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