Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A major EBNA1 variant from Asian EBV isolates shows enhanced transcriptional activity compared to prototype B95.8.

Virus research - 1 Mar 2008

Do Nguyen-Van, Ingemar Ernberg, Phi Phan-Thi Phi, Jenny Almqvist, Chinh Tran-Thi, Zeng Yixin, Hu Lifu

Abstract excerpt

Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA1) has an instrumental role in maintaining EBV latent infection by controlling EBV episome replication and regulating viral transcription. It is a ubiquitously expressed protein during latent viral infection and in EBV-associated tumors. The EBNA1 C-terminus interacts functionally with the Qp and Cp that control viral gene expression in latency I/II and III,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epstein-Barr Virus Infections
Share to Epstein-Barr Virus Nuclear Antigens

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Reporter

Share to Herpesvirus 4, Human

Share to Nasopharyngeal Neoplasms

Share to Response Elements

Share to Transcriptional Activation

Share to Vietnam

Source

Identifiers

PMID: 18096263
DOI: 10.1016/j.virusres.2007.10.020

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A major EBNA1 variant from Asian EBV isolates shows enhanced transcriptional activity compared to prototype B95.8.PMID 18096263Read ↗

The enhanced transcriptional activity of the V-val subtype of Epstein-Barr virus nuclear antigen 1 in epithelial cell lines.Semantic proximity Read ↗

Epstein-Barr virus genetic variation in Vietnamese patients with nasopharyngeal carcinoma: full-length analysis of LMP1.Semantic proximity Read ↗

EBNA-1 sequence variations reflect active EBV replication and disease status or quiescent latency in lymphocytes.Semantic proximity Read ↗

Functional advantage of NPC-related V-val subtype of Epstein-Barr virus nuclear antigen 1 compared with prototype in epithelial cell line.Semantic proximity Read ↗

[Functions of V-val subtype of Epstein-Barr nuclear antigen 1].Semantic proximity Read ↗

Carcinoma-risk variant of EBNA1 deregulates Epstein-Barr Virus episomal latencySemantic proximity Read ↗

Sequence variations in EBNA-1 may dictate restriction of tissue distribution of Epstein-Barr virus in normal and tumour cells.Semantic proximity Read ↗

High risk Epstein‐Barr virus variants characterized by distinct polymorphisms in the EBER locus are strongly associated with nasopharyngeal carcinomaSemantic proximity Read ↗

Specific latent membrane protein 1 gene sequences in type 1 and type 2 Epstein-Barr virus from nasopharyngeal carcinoma in Hong KongSemantic proximity Read ↗

Molecular Characterization of the Epstein-Barr Virus in Malignant Tumors of Different Origins: An Emphasis on EBER Promoter Value for EBV Classification.Semantic proximity Read ↗

Characterization of a cancer-associated Epstein-Barr virus EBNA1 variant reveals a novel interaction with PLOD1 and PLOD3.Semantic proximity Read ↗

Genomic Sequencing and Comparative Analysis of Epstein-Barr Virus Genome Isolated from Primary Nasopharyngeal Carcinoma BiopsySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.