Article
Progression to type 1 diabetes and autoantibody positivity in relation to HLA-risk genotypes in children participating in the ABIS study.
Pediatric diabetes - 1 Jun 2008
Gullstrand Camilla, Wahlberg Jeanette, Ilonen Jorma, Vaarala Outi, Ludvigsson Johnny
Abstract excerpt
BACKGROUND: Autoantibodies against beta-cell antigens together with human leukocyte antigen (HLA)-risk genotypes are used as predictive markers for type 1 diabetes (T1D). In this study, we have investigated the role of HLA-risk and -protective genotypes for development of beta-cell autoantibodies and progression to T1D in healthy children. METHODS: T1D-related HLA genotypes and autoantibodies against glutamic...
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