Article
Ryanodine receptor arrays: not just a pretty pattern?
Trends in cell biology - 1 Apr 2008
Yin Chang-Cheng, D'Cruz Leon G, Lai F Anthony
Abstract excerpt
Ryanodine receptors (RyRs) are colossal membrane protein complexes that reside in the endoplasmic reticulum of skeletal and cardiac muscle myocytes and neurons, in addition to many non-excitable cells. They comprise high-conductance ion channels that mediate the massive release of Ca2+ ions from the endoplasmic reticulum into the cytoplasm. This is the trigger for contraction during each muscle...
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