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Article

Structural Details of the Ryanodine Receptor Calcium Release Channel and Its Gating Mechanism.

Advances in experimental medicine and biology - 1 Jan 2017

Willegems Katrien, Efremov Rouslan G

Abstract excerpt

Ryanodine receptors (RyRs) are large intracellular calcium release channels that play a crucial role in coupling excitation to contraction in both cardiac and skeletal muscle cells. In addition, they are expressed in other cell types where their function is less well understood. Hundreds of mutations in the different isoforms of RyR have been associated with inherited myopathies and cardiac arrhythmia disorders....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29594862
DOI: 10.1007/978-3-319-55858-5_8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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