Article
International stroke genetics consortium recommendations for studies of genetics of stroke outcome and recovery.
International journal of stroke : official journal of the International Stroke Society - 1 Mar 2022
Lindgren Arne G, Braun Robynne G, Juhl Majersik Jennifer, Clatworthy Philip, Mainali Shraddha, Derdeyn Colin P, Maguire Jane, Jern Christina, Rosand Jonathan, Cole John W, Lee Jin-Moo, Khatri Pooja, Nyquist Paul, Debette Stéphanie, Keat Wei Loo, Rundek Tatjana, Leifer Dana, Thijs Vincent, Lemmens Robin, Heitsch Laura, Prasad Kameshwar, Jimenez Conde Jordi, Dichgans Martin, Rost Natalia S, Cramer Steven C, Bernhardt Julie, Worrall Bradford B, Fernandez-Cadenas Israel
Abstract excerpt
Numerous biological mechanisms contribute to outcome after stroke, including brain injury, inflammation, and repair mechanisms. Clinical genetic studies have the potential to discover biological mechanisms affecting stroke recovery in humans and identify intervention targets. Large sample sizes are needed to detect commonly occurring genetic variations related to stroke brain injury and recovery. However, this...
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