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Article

Synergistic effect of two oxidative stress-related genes (heme oxygenase-1 and GSK3β) on the risk of Parkinson's disease.

European journal of neurology - 1 May 2010

Infante J, García-Gorostiaga I, Sánchez-Juan P, Sierra M, Martín-Gurpegui J L, Terrazas J, Mateo I, Rodríguez-Rodríguez E, Berciano J, Combarros O

Abstract excerpt

BACKGROUND: Oxidative stress is a central factor in the pathogenesis of Parkinson's disease (PD). Heme oxygenase-1 (HO-1) is an antioxidant protein expressed in response to oxidative challenge, and its expression levels are inversely correlated with glycogen synthase kinase-3beta (GSK3beta) activ...

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Source

Identifiers

PMID: 20039940
DOI: 10.1111/j.1468-1331.2009.02908.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20039940-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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