Article
Genetic analysis of tumor necrosis factor-alpha (TNF-alpha) G-308A and Saitohin Q7R polymorphisms with Alzheimer's disease.
Journal of the neurological sciences - 15 Jul 2008
Wang Binbin, Zhou Sirui, Yang Ze, Xie Yan-Chen, Wang Jing, Zhang Peng, Lv Zeping, Zheng Chenguang, Ma Xu
Abstract excerpt
Neuroinflammation and abnormal phosphorylation of TAU proteins have been implicated in the etiology of Alzheimer's disease (AD). Several studies have suggested the G-308A promoter polymorphism in one of the proinflammatory cytokine genes tumor necrosis factor-alpha (TNF-alpha) encoding TNF-alpha...
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