Article
Evolutionary analysis of genes of two pathways involved in placental malaria infection.
Human genetics - 1 May 2008
Sikora Martin, Ferrer-Admetlla Anna, Mayor Alfredo, Bertranpetit Jaume, Casals Ferran
Abstract excerpt
Placental malaria is a special form of malaria that causes up to 200,000 maternal and infant deaths every year. Previous studies show that two receptor molecules, hyaluronic acid and chondroitin sulphate A, are mediating the adhesion of parasite-infected erythrocytes in the placenta of patients, which is believed to be a key step in the pathogenesis of the disease. In this study, we aimed at identifying sites of...
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