Article

Three hallmarks of malaria-induced selection in human genomes

2020-07-07

Abstract excerpt

Malaria has plausibly been the single strongest selective pressure on our species. Many of the best-characterized cases of adaptive evolution in humans are in genes tied to malaria resistance. However, the complex evolutionary patterns at these genes are poorly captured by standard scans for non-neutral evolution. Here we present three new statistical tests for selection based on population genetic patterns that a...

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Literature Corpus work: f04727ca-a4fb-5dc2-92b2-6bd18f500595
DOI: 10.1101/2020.07.07.170092

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