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Article

Population-specific adaptation in malaria-endemic regions of asia.

Journal of bioinformatics and computational biology - 1 Dec 2021

Gusareva Elena S, Lorenzini Paolo Alberto, Binte Ramli Nurul Adilah, Ghosh Amit Gourav, Kim Hie Lim

Abstract excerpt

Evolutionary mechanisms of adaptation to malaria are understudied in Asian endemic regions despite a high prevalence of malaria in the region. In our research, we performed a genome-wide screening for footprints of natural selection against malaria by comparing eight Asian population groups from malaria-endemic regions with two non-endemic population groups from Europe and Mongolia. We identified 285 adaptive...

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PMID: 34753405
DOI: 10.1142/S0219720021400060

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