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Article

Deletion of the protein kinase A/protein kinase G target SMTNL1 promotes an exercise-adapted phenotype in vascular smooth muscle.

The Journal of biological chemistry - 25 Apr 2008

Wooldridge Anne A, Fortner Christopher N, Lontay Beata, Akimoto Takayuki, Neppl Ronald L, Facemire Carie, Datto Michael B, Kwon Ashley, McCook Everett, Li Ping, Wang Shiliang, Thresher Randy J, Miller Sara E, Perriard Jean-Claude, Gavin Timothy P, Hickner Robert C, Coffman Thomas M, Somlyo Avril V, Yan Zhen, Haystead Timothy A J

Abstract excerpt

In vivo protein kinases A and G (PKA and PKG) coordinately phosphorylate a broad range of substrates to mediate their various physiological effects. The functions of many of these substrates have yet to be defined genetically. Herein we show a role for smoothelin-like protein 1 (SMTNL1), a novel...

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Share to Cyclic AMP-Dependent Protein Kinases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Muscle Fibers, Skeletal

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Source

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Identifiers

PMID: 18310078
DOI: 10.1074/jbc.M708628200
PMCID: PMC2431077

Genes

SMTNL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18310078-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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