Article
Combined linkage and association mapping of quantitative trait Loci with missing completely at random genotype data.
Behavior genetics - 1 May 2008
Fan Ruzong, Liu Lian, Jung Jeesun, Zhong Ming
Abstract excerpt
In genetics study, the genotypes or phenotypes can be missing due to various reasons. In this paper, the impact of missing genotypes is investigated for high resolution combined linkage and association mapping of quantitative trait loci (QTL). We assume that the genotype data are missing completely at random (MCAR). Two regression models, "genotype effect model" and "additive effect model", are proposed to model...
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