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Article

Effects of missing marker and segregation distortion on QTL mapping in F2 populations.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik - 1 Oct 2010

Zhang Luyan, Wang Shiquan, Li Huihui, Deng Qiming, Zheng Aiping, Li Shuangcheng, Li Ping, Li Zhonglai, Wang Jiankang

Abstract excerpt

Missing marker and segregation distortion are commonly encountered in actual quantitative trait locus (QTL) mapping populations. Our objective in this study was to investigate the impact of the two factors on QTL mapping through computer simulations. Results indicate that detection power decreases with increasing levels of missing markers, and the false discovery rate increases. Missing markers have greater...

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PMID: 20535442
DOI: 10.1007/s00122-010-1372-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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