Article
Quantifying the amount of missing information in genetic association studies.
Genetic epidemiology - 1 Dec 2006
Nicolae Dan L
Abstract excerpt
Many genetic analyses are done with incomplete information; for example, unknown phase in haplotype-based association studies. Measures of the amount of available information can be used for efficient planning of studies and/or analyses. In particular, the linkage disequilibrium (LD) between two sets of markers can be interpreted as the amount of information one set of markers contains for testing allele...
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