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Article

Vesicular glutamate transporter 3 is required for synaptic transmission in zebrafish hair cells.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 27 Feb 2008

Obholzer Nikolaus, Wolfson Sean, Trapani Josef G, Mo Weike, Nechiporuk Alex, Busch-Nentwich Elisabeth, Seiler Christoph, Sidi Samuel, Söllner Christian, Duncan Robert N, Boehland Andrea, Nicolson Teresa

Abstract excerpt

Hair cells detect sound and movement and transmit this information via specialized ribbon synapses. Here we report that asteroid, a gene identified in an ethylnitrosourea mutagenesis screen of zebrafish larvae for auditory/vestibular mutants, encodes vesicular glutamate transporter 3 (Vglut3). A splice site mutation in exon 2 of vglut3 results in a severe truncation of the predicted protein product and...

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Identifiers

PMID: 18305245
DOI: 10.1523/JNEUROSCI.5230-07.2008
PMCID: PMC6671858

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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