Article
gemini encodes a zebrafish L-type calcium channel that localizes at sensory hair cell ribbon synapses.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 28 Apr 2004
Sidi Samuel, Busch-Nentwich Elisabeth, Friedrich Rainer, Schoenberger Ulrike, Nicolson Teresa
Abstract excerpt
L-type Ca2+ channels (LTCCs) drive the bulk of voltage-gated Ca2+ entry in vertebrate inner ear hair cells (HCs) and are essential for mammalian auditory processing. LTCC currents have been implicated in neurotransmitter release at the HC afferent active zone, the ribbon synapse. It is likely that LTCCs play a direct role in vesicle fusion; however, the subcellular localization of the channels in HCs has not been...
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