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Article

Polymorphisms in HIV-1 subtype C proteases and the potential impact on protease inhibitors.

Tropical medicine & international health : TM & IH - 1 Feb 2008

Bessong Pascal Obong

Abstract excerpt

OBJECTIVES: (i) To review data on the genetic profile of the protease (PR) gene of human immunodeficiency virus (HIV)-1-C primary isolates relative to HIV-1-B; (ii) to examine data on the susceptibility of HIV-1-C isolates harbouring polymorphisms to PR inhibitors (PI) and the development of resistance; and (iii) to identify gaps required for an improved understanding of the role of polymorphisms in resistance...

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Identifiers

PMID: 18304259
DOI: 10.1111/j.1365-3156.2007.01984.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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