Article
Emergence of drug resistance-associated mutations in HIV-1 subtype C protease gene in north India.
Virus genes - 1 Dec 2013
Azam Mohd, Malik Abida, Rizvi Meher, Singh Supriya, Gupta Poonam, Rai Arvind
Abstract excerpt
A major cause of anti-retroviral therapy (ART) failure is the drug resistance-associated mutations in polymerase gene of HIV-1. Paucity of data regarding potential drug resistance to protease inhibitors (PIs) prompted us to carry out this study. Drug resistance (DR) genotyping of the entire protease gene was performed in 104 HIV-1 ART-naive and first-line ART-experienced patients. The DR pattern was analyzed...
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