Article
Characterization of HIV type 1 subtype C protease gene: selection of L63P mutation in protease inhibitor-naive Indian patients.
AIDS research and human retroviruses - 1 Nov 2011
Neogi Ujjwal, Sahoo Pravat Nalini, Kumar Ravi, De Costa Ayesha, Shet Anita
Abstract excerpt
Significant subtype-specific differences were observed in the protease (PR) region of the HIV-1 pol gene. Most of the previous studies were restricted to subtype B, although subtype C accounts for more than 50% of HIV infections worldwide. In this study we characterized PR sequences from primary clinical isolates from protease inhibitor (PI)-naive patients in South India (n=39) as well as database-derived HIV-1...
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