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Article

Optimization of the Affymetrix GeneChip Mapping 10K 2.0 Assay for routine clinical use on formalin-fixed paraffin-embedded tissues.

Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Mar 2008

Lyons-Weiler Maureen, Hagenkord Jill, Sciulli Christin, Dhir Rajiv, Monzon Federico A

Abstract excerpt

The use of chromosomal copy number changes as markers for tumor behavior or as prognostic markers for patient outcome has been suggested. However, current clinically used technologies cannot perform genome-wide assessment of chromosome copy number and analysis of loss of heterozygosity in the same assay for paraffin-embedded tissue. We have optimized the Affymetrix GeneChip Mapping Assay for the 10K 2.0 array for...

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PMID: 18303412
DOI: 10.1097/PDM.0b013e31815aca30

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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