Article
Reproducibility and performance of virtual karyotyping with SNP microarrays for the detection of chromosomal imbalances in formalin-fixed paraffin-embedded tissues.
Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Sept 2010
Alvarez Karla, Kash Shera F, Lyons-Weiler Maureen A, Kim Hyun-Jung, Peterson Leif E, Mathai Benita, Hagenkord Jill M, Monzon Federico A
Abstract excerpt
BACKGROUND: Chromosomal imbalances are commonly seen in cancer and inherited genetic diseases. These imbalances may assist in the diagnosis, prognosis, and/or therapeutic management of certain neoplasms. Several methods for detecting chromosomal imbalances, such as, fluorescent in situ hybridizat...
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