Article
Whole genome SNP arrays as a potential diagnostic tool for the detection of characteristic chromosomal aberrations in renal epithelial tumors.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 May 2008
Monzon Federico A, Hagenkord Jill M, Lyons-Weiler Maureen A, Balani Jyoti P, Parwani Anil V, Sciulli Christin M, Li Jia, Chandran Uma R, Bastacky Sheldon I, Dhir Rajiv
Abstract excerpt
Renal tumors with complex or unusual morphology require extensive workup for accurate classification. Chromosomal aberrations that define subtypes of renal epithelial neoplasms have been reported. We explored if whole-genome chromosome copy number and loss-of-heterozygosity analysis with single nucleotide polymorphism (SNP) arrays can be used to identify these aberrations and classify renal epithelial tumors. We...
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