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Article

Patterns of inheritance of the symptoms of Huntington's disease suggestive of an effect of genomic imprinting.

Journal of medical genetics - 1 Apr 1991

Ridley R M, Frith C D, Farrer L A, Conneally P M

Abstract excerpt

The interaction of symptomatology (rigidity/chorea) in Huntington's disease (HD) with age of onset (AO) was examined using data from the Research Roster for Huntington's Disease Patients and Families. It was shown that AO varies between families and between paternal and maternal transmission and that rigidity is associated specifically with very early onset, major anticipation, paternal transmission, and young...

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Identifiers

PMID: 1830339
DOI: 10.1136/jmg.28.4.224
PMCID: PMC1016822

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Source receipt: pubmed, retrieved 7 Sept 2026.

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