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Article

Genetic analysis of polymorphisms in the kalirin gene for association with age-at-onset in European Huntington disease patients.

BMC medical genetics - 21 Jun 2012

Tsai Yu-Chun, Metzger Silke, Riess Olaf, Soehn Anne S, Nguyen Huu Phuc

Abstract excerpt

BACKGROUND: Huntington disease (HD) is caused by an expanded CAG repeat in the HD gene. Although the length of the CAG repeat strongly correlates with the age-at-onset (AAO), AAO in HD individuals may differ dramatically in spite of similar expanded CAG repeat lengths. Additional genetic or envir...

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Source

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Identifiers

PMID: 22720673
DOI: 10.1186/1471-2350-13-48
PMCID: PMC3433364

Genes

KALRN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22720673-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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