Article
Different phenotypic expression in monozygotic twins with Huntington disease.
American journal of medical genetics. Part A - 1 Jan 2004
Anca M H, Gazit E, Loewenthal R, Ostrovsky O, Frydman M, Giladi N
Abstract excerpt
Monozygotic (MZ), 46-year-old, male twins, carrying the same Huntington disease (HD) mutation, presented with a different clinical course. In one of the twins, the disease process started at the age of 32 years with chorea, dysarthria, and a depressed mood. Over 14 years, the disease progressed to total functional dependence. The second twin presented at age 35 with gait disturbances. His behavior became...
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