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Article

Characterization of a temperature-sensitive mutation that impairs the function of yeast tRNA nucleotidyltransferase.

Yeast (Chichester, England) - 1 Mar 2008

Shan Xunying, Russell Tara A, Paul Scott M, Kushner David B, Joyce Paul B M

Abstract excerpt

ATP(CTP) : tRNA nucleotidyltransferase catalyses the posttranscriptional addition of cytidine, cytidine and adenosine to the 3' ends of tRNAs. Previously, a temperature-sensitive phenotype in Saccharomyces cerevisiae resulting from a mutation in the CCA1 gene coding for this enzyme was identified. Here, we show that a single guanine-to-adenine transition in cca1-1 generates the temperature-sensitive phenotype....

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Identifiers

PMID: 18302315
DOI: 10.1002/yea.1582

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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